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Misrani A, Tabassum S, Yang L (2021) Mitochondrial dysfunction and oxidative stress in Alzheimers disease

The AEOL series and pentaazamacrocyclic ligand-based mimetics (SC series and M404 series), on the other hand, are more specialized toward O 2 (though many can also address other ROS as well) and generally lack catalase-like activity (targeted to eliminate H 2 O 2 ), and this may limit their therapeutic use (e.g., to more acute conditions such as lung injury or effects of ionizing radiation) (Liang et al., 2007

This downregulated gene can mitigate the effects of IL-1 on the production of proinflammatory mediators, matrix MMP activity, and proteoglycan synthesis (Amin 2000)

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The S-glutathionylation is a process in which the interaction between GSSG and cysteinyl residues of proteins results in the formation of mixed disulfides (22)